Colostrum Secrets: Boosting Puppy Immunity and Growth from Day One

Over the years, I’ve delved deeply into the topic of colostrum through various blogs, reflecting the burgeoning scientific interest and publications that have emerged over the past decade. This surge in research has revolutionized our approach to newborn puppy care in kennels and veterinary settings alike. And recently, I discovered an intriguing method known as the “weigh-suckle-weigh technique”. This discovery not only piqued my curiosity but also inspired a practical idea that I am excited to share here. If you’re keen on understanding the benefits of colostrum, ways to support immunity in puppies, and strategies for optimal colostrum intake to foster long-term health and growth, keep reading!


  1. What is Colostrum and How Does It Benefit Puppies?
    1. Defining Colostrum and Its Importance in Canine Health
    2. The Nutritional Content of Colostrum
    3. The Role of Colostrum in Puppy Immunity
  2. How Do Puppies Receive and Utilize Colostrum?
    1. Natural Colostrum Intake from Mothers
    2. The Timing and Importance of Early Colostrum Intake
    3. Assessing Adequate Colostrum Intake in Newborn Puppies
    4. What If a Puppy Can’t Get Colostrum Naturally?

What is Colostrum and How Does It Benefit Puppies?

A veterinarian holding a vial of colostrum, illustrating the topic of colostrum and its benefits for puppies.

Defining Colostrum and Its Importance in Canine Health

Colostrum, often heralded as the ‘first milk’, is a vital form of nourishment that mother dogs provide during the initial hours after a puppy’s birth. 

But what exactly makes colostrum so crucial for canine health?

The benefits of colostrum for puppies extend well beyond basic nutrition. 

It is packed with high concentrations of immunoglobulins—specifically IgA, IgG, and IgM—which are critical for its immune system development

It contains growth hormones and other bioactive compounds that foster organ development and overall vitality. 

These initial bacteria are essential, as they begin to colonize the puppy’s digestive tract, establishing a foundational microbiome

A post on Threads from Dr EMMANUEL FONTAINE on colostrum as a source of bacteria for newborn puppies.

This microbial colonization not only aids in the digestion and absorption of nutrients but also fortifies the puppy’s defenses against pathogens, shaping a robust immune response that supports the puppy throughout its early life and beyond. 

The Nutritional Content of Colostrum

A detailed scientific illustration of colostrum molecules and immune cells interacting, symbolizing the nutritional content of colostrum.

This initial secretion from mother dogs is far more nutrient-dense than regular milk, designed specifically to jumpstart the health and development of newborn puppies.

The nutritional spectrum of colostrum is impressive, featuring a high concentration of proteins, essential fats, vitamins, and minerals. These components are critical for energy and the building of tissues.

The presence of growth factors, like insulin-like growth factors (IGFs), further supports tissue development and organ maturation, laying the foundation for robust health.

Additionally, colostrum is a source of various bioactive compounds with anti-inflammatory properties (lactoferrin is always one that comes to my mind), which help protect the delicate digestive system of the newborn puppy. 

These compounds ensure that the gut effectively absorbs nutrients while maintaining a healthy balance of flora, which is essential for long-term digestive health.

The Role of Colostrum in Puppy Immunity

An expanded view of antibodies within colostrum, represented artistically

Packed with vital immunoglobulins, colostrum provides the antibodies necessary to combat various infectious diseases. 

This is due to the specific type of placentation in dogs, which allows a small but crucial transfer of immunity before birth, ensuring that puppies are not entirely defenseless upon arrival.

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It includes antibodies against diseases for which the mother has been vaccinated, as well as those she has naturally encountered. Furthermore, antibodies against potential environmental pathogens to which the mother has been exposed are also transferred. 

This underscores the critical importance of optimizing colostrum production through proper maternal nutrition and vaccination. Such measures are essential to enhance the immune transfer to newborn puppies and to safeguard their early days.

Dog breeders sometimes conduct a test known as a “nomograph” during gestation. 

This test assesses the immune status of the mother and helps predict the optimal timing for vaccinating puppies based on their expected immunity gap. 

However, research in canine colostrum reveals significant variability in antibody concentration across different mammary glands during lactation. 

Such disparities imply that the quantity of antibodies each puppy receives can differ substantially—studies indicate that up to 20% of puppies may not receive adequate immunity through colostrum alone. 

How Do Puppies Receive and Utilize Colostrum?

A serene nursery room where a mother dog, a golden retriever, is nursing her newborn puppies.

Natural Colostrum Intake from Mothers

Colostrum can be present in the mother’s mammary glands up to two weeks before parturition. However, its availability can vary greatly. 

For dog breeders, a crucial step is ensuring the presence of colostrum as soon as the female begins the birthing process. 

This approach highlights the importance of colostrum availability as a key factor in neonatal puppy care, emphasizing its critical role in the successful rearing of healthy puppies.

A post from Dr EMMANUEL FONTAINE on Threads on how to evaluate colostrum quality in the canine species

In dogs, the best practical method to ascertain whether a substance is colostrum is by its color; typically, colostrum exhibits a yellowish hue, in contrast to the white color of regular milk. 

Unfortunately, there are no clinical tests readily available to measure the concentration of immunoglobulins in colostrum; such tests are reserved for research purposes. 

The Timing and Importance of Early Colostrum Intake

A microscopic view of colostrum molecules, artistically represented as glowing orbs connected by shimmering lines, to symbolize its rich nutritional content

Colostrum absorption, especially for the development of the immune system, is undeniably a matter of precise timing. 

As previously mentioned, colostrum is typically secreted in the mammary glands during the first 24 hours of lactation. In cases where colostrum is present several days before parturition, it ideally remains available unless prematurely removed or consumed by other puppies—a scenario to be avoided to prevent nursing from a pregnant mother. 

I always wondered if this early production has an impact on colostrum quality at the time of parturition… however, the current scientific literature does not provide conclusive evidence on this matter from what I have seen.

The ability of puppies to absorb these vital antibodies from colostrum is time-sensitive

This makes the timing of the first feed not just beneficial, but critical. 

A post from Dr EMMANUEL FONTAINE on Threads on the timing of colostrum absorption in newborn puppies

Assessing Adequate Colostrum Intake in Newborn Puppies

A scientific representation of antibodies, depicted as glowing geometric shapes, defending against dark, amorphous virus particles, symbolizing their role in puppy immunity.

I recently came across an abstract from the 2023 European Conference in Dog and Cat Reproduction that introduced a fascinating concept: the “weigh-suckle-weigh method” for newborn puppies. 

Their findings revealed that weight gain during a single suckling session could range dramatically (from 0 to 28.5g, with a median value of 2.5g), underscoring the variability in colostrum intake across different litters and conditions.

But this is just the beginning of this short story! 

A post on Threads from Dr EMMANUEL FONTAINE on the use of frozen colostrum in puppies and kittens.

Drawing from this, I used what I could find in the scientific literature… and did the math to determine the average weight of 1.5mL of colostrum actually! 

Considering this, the weigh-suckle-weigh technique can be practical for breeders:

1. Weigh the puppy immediately after birth, before it begins to nurse.

2. Allow the puppy to nurse from its mother.

3. Weigh the puppy again after nursing. To have received sufficient colostrum, the puppy should exhibit a weight gain of approximately 1.545-1.575g per 100g of body weight.

Don’t want to do the math? Download my Colostrum Intake Calculator for Puppies!

Colostrum Intake Calculator developed by Dr EMMANUEL FONTAINE

This method not only promises a practical approach to ensure puppies are adequately nourished right after birth but also highlights the importance of having accurate scales in kennel maternity settings

A post on Threads from Dr EMMANUEL FONTAINE about the specifications of the weight scale to use in a kennel maternity.

While additional research is needed to refine this technique and fully understand its implications for neonatal survival, the initial results are promising and offer a practical interim solution for breeders committed to optimizing the health outcomes of their litters.

What If a Puppy Can’t Get Colostrum Naturally?

The early moments of puppy immunity development, showing a close-up of a puppy’s paw gently touching its mother’s, symbolizing the transfer of antibodies through colostrum.

When natural colostrum intake is not an option for newborn puppies, two main alternatives can be considered to ensure they receive the crucial early immunity support they need.

Collecting colostrum from a mother dog is relatively straightforward, and it can be stored in small plastic vials and kept frozen for approximately a year. 

A post on Threads from Dr EMMANUEL FONTAINE on how to use frozen colostrum

This provides a valuable backup should a female not produce colostrum before giving birth.

Ideally, this colostrum would originate from a female within the same environment or kennel, ensuring that the puppies receive antibodies relevant to the pathogens present in their specific environment. 

Interested to learn more about canine neonatology? Download my free ebook on the topic

After the puppies’ initial nursing and during the first 24 hours postpartum, colostrum can be collected and stored in anticipation of future needs. 

Notably, the first milk from a female experiencing a pseudo-pregnancy is of equivalent quality to normal colostrum and can also be collected for this purpose. 

The second alternative is a dedicated canine milk replacer, particularly one supplemented with immunoglobulins. 

In some countries, specific milk replacers are available that contain antibodies against major threats like E.coli (number 1 infectious cause of neonatal mortality in newborn puppies) and canine parvovirus, which are significant causes of mortality in weaning puppies

These milk replacers often include maltodextrin, which is beneficial for premature human babies due to its energy-releasing properties, making it equally advantageous for newborn puppies. 

This is my preferred option when natural canine colostrum is unavailable. 

However, if such a product is not accessible, a standard canine milk replacer still offers a viable solution

It’s important to mention that while serum administration has been explored as an alternative, current evidence suggests it is not a suitable replacement for colostrum in puppies. 

Similarly, using bovine or equine colostrum is not recommended; although it may provide some benefits to the digestive tract, it lacks the canine-specific antibodies necessary for effective immunity support in puppies. 

These alternatives do not adequately address the unique needs of canine neonates and should not be relied upon for ensuring their health and development.

Read my previous blog on this topic: No colostrum… what about serum? 


In recent years, our understanding of canine colostrum and its critical role in neonatal health has grown immensely. The strategies and tools that have emerged from this knowledge, such as the weigh-suckle-weigh method discussed in this blog, are not only simple but incredibly effective in my opinion. Implementing these practices in breeding kennels can significantly improve neonatal survival rates, showcasing the practical benefits of veterinary research.

Canine neonatology continues to be a dynamic field within canine reproduction, with new discoveries on the horizon that promise to enhance our practices further. The potential for future advancements is exciting, and I am committed to keeping you informed. As we learn more, I look forward to sharing these developments through my newsletter and on this blog, helping breeders and veterinary professionals enhance the care and outcomes for puppies from their very first moments of life. Stay tuned—there’s much more to come in the world of canine neonatal care for sure!

One of the most common challenge we encounter in breeding kennels is NEONATAL MORTALITY. 

It can be very frustrating… even heart-breaking.

Good news though : you can do something about it ! 

We now have more knowledge than ever in this discipline. 

In recent years, new research brought us a much better understanding of what can be done to optimize the health of newborn puppies.

By taking this course, this is what you will learn indeed ! 

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